DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 719277-30-2
Molecular formula: C14H15NO3S
Molecular weight: 277.3
Purity: >98% (HPLC)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO (10mg/ml).
InChiKey: RLEOCVDWLAYGRX-AUWJEWJLSA-N
SMILES: O=C(C)/C=C1SC2=CC=C(OC(C)=O)C=C2N\1CC
Description:
Cell permeable ATP-competitive DYRK1A and DYRK1B inhibitor. Inhibits phosphorylation of Tau-protein and rescues repressed calcineurin/NFAT signaling. Recovers Xenopus embryos from head malformation induced by DYRK1A overexpression in vivo.