bs-75552C
[Life Science]
TBB
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 17374-26-4
Molecular formula: C6HBr4N3
Molecular weight: 434.7
Purity: >98% (HPLC)
Appearance: Solid.
Solubility: Soluble in DMSO (20mg/ml).
InChiKey: OMZYUVOATZSGJY-UHFFFAOYSA-N
SMILES: BrC1=C(Br)C(Br)=C(Br)C2=C1N=NN2
Molecular formula: C6HBr4N3
Molecular weight: 434.7
Purity: >98% (HPLC)
Appearance: Solid.
Solubility: Soluble in DMSO (20mg/ml).
InChiKey: OMZYUVOATZSGJY-UHFFFAOYSA-N
SMILES: BrC1=C(Br)C(Br)=C(Br)C2=C1N=NN2
Description:
ATP/GTP-competitive cell permeable casein kinase II (CK2) inhibitor (IC50=0.9µM for rat liver. Less potently inhibits CCK2/cyclin A, GSK3beta and phosphorylase kinase (IC50=15.6, 11.2 and 8.7µM, respectively). Binds to the Val66 residue of CK2 and inhibits the binding of ATP/GTP. Moderate DYRK1A inhibitor (IC50=4.4µM). Induces caspase-dependent apoptosis and degrades hematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells.
Size: 5mg,25mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.