DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 120068-37-3
Molecular formula: C12H4Cl2F6N4OS
Molecular weight: 437.2
Purity: >98% (NMR)
Appearance: White to yellow solid.
Solubility: Soluble in DMSO, methanol, ethanol or acetone. Insoluble in water.
InChiKey: ZOCSXAVNDGMNBV-UHFFFAOYSA-N
SMILES: ClC1=C(N2N=C(C#N)C(S(C(F)(F)F)=O)=C2N)C(Cl)=CC(C(F)(F)F)=C1
Description:
Alzheimer inducing agent (Alzheimerogen). Potent GABA receptor alpha-4 subunit and beta-3 subunit inhibitor. Broad-range insecticide. Blocks GABA A-gated chloride channels and glutamate-activated chloride channels (GluCls) in the central nervous system, resulting in overexcitation of the insects nervous system and muscles. Induces oxidative stress in mouse kidney and brain. Increases CYP1A1, CYP2B6, CYP3A4 and CYP3A5 transcript, protein and enzyme activity levels.