bs-75522C
[Life Science]
Regorafenib [BAY 73-4506]
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 755037-03-7
Molecular formula: C21H15ClF4N4O3
Molecular weight: 482.8
Purity: >98% (HPLC)
Appearance: Light pink to white solid.
Solubility: Soluble in DMSO (>50mg/ml). Slightly soluble in ethanol (1mg/ml). Insoluble in water.
InChiKey: FNHKPVJBJVTLMP-UHFFFAOYSA-N
SMILES: CNC(=O)C1=CC(OC2=CC(F)=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)=CC=N1
Molecular formula: C21H15ClF4N4O3
Molecular weight: 482.8
Purity: >98% (HPLC)
Appearance: Light pink to white solid.
Solubility: Soluble in DMSO (>50mg/ml). Slightly soluble in ethanol (1mg/ml). Insoluble in water.
InChiKey: FNHKPVJBJVTLMP-UHFFFAOYSA-N
SMILES: CNC(=O)C1=CC(OC2=CC(F)=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2)=CC=N1
Description:
Orally bioavailable potent antitumor, antiangiogenic, antiproliferative and antineoplastic agent. Multi-target kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRbeta, Kit, RET and Raf-1 with IC50 values of 13, 4.2, 46, 22, 7, 1.5 and 2.5nM, respectively.
Size: 5mg,25mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.