bs-75514C
[Life Science]
Glyburide (USP)
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 10238-21-8
Molecular formula: C23H28ClN3O5S
Molecular weight: 494
Purity: >98%
Appearance: White to off-white solid.
Solubility: Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol (gentle warming).
InChiKey: ZNNLBTZKUZBEKO-UHFFFAOYSA-N
SMILES: COC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
Molecular formula: C23H28ClN3O5S
Molecular weight: 494
Purity: >98%
Appearance: White to off-white solid.
Solubility: Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol (gentle warming).
InChiKey: ZNNLBTZKUZBEKO-UHFFFAOYSA-N
SMILES: COC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
Description:
Antidiabetic compound. Binds to and activates the ATP-sensitive potassium channels (KATP) inhibitory regulatory subunit sulfonylurea receptor 1 (SUR1). Causes cell membrane depolarization and opening of voltage-dependent calcium channel. Increases intracellular calcium and stimulates insulin secretion in beta cells NLRP3 inflammasome inhibitor. Broad-spectrum ATP-binding cassette (ABC) transporter inhibitor. Shown to have anti-leishmanial activity. Potential inhibitor of collagenases.
Size: 1g, 5g, , 10g1g, 5g, , 10g
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.