DATASHEET
Formulation
Solid
Storage:
Stable for 1 year after receipt when stored at -20°C.
Product Information:
CAS Number: 179324-69-7
Molecular formula: C19H25BN4O4
Molecular weight: 384.2
Purity: >97% (NMR)
Appearance: White solid.
Solubility: Soluble in DMSO, ethanol or methanol. Slightly soluble in water.
InChiKey: GXJABQQUPOEUTA-RDJZCZTQSA-N
SMILES: CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=NC=CN=C1)B(O)O
Description:
Highly potent, selective and reversible cell permeable inhibitor of the proteasome. Inhibits the chymotrypsin-like and caspase-like peptidase activity of the proteasome. Calpain and cathepsin inhibitor. Autophagy activator. Anticancer compound. Inhibits proliferation and migration of several tumor cell lines with nanomolar potency. Apoptosis inducer.