DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 41575-94-4
Molecular formula: C6H12N2O4Pt
Molecular weight: 371.3
Purity: >98%
Appearance: White to off-white powder.
Solubility: Soluble in water.
InChiKey: YAYRGNWWLMLWJE-UHFFFAOYSA-L
SMILES: N[Pt]1(N)OC(=O)C2(CCC2)C(=O)O1
Description:
Potent platinum-based antineoplastic agent. Analog of cisplatin (Prod. No. bs-75499C) with reduced nephrotoxicity and higher stability. Antitumor agent. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Interferes with cell division by mitosis. The damaged DNA elicits DNA repair mechanisms, which in turn activate apoptosis when repair is impossible. Apoptosis inducer. Enhances radiation-induced single-strand DNA breakage.