bs-75497C
[Life Science]
cGAMP . 2Na [STING Ligand]
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C. Working aliquots are stable for up to 6 months when stored at -20°C.
Product Information:
CAS Number: 849214-04-6 (free acid)
Molecular formula: C20H24N10O13P2 . 2Na
Molecular weight: 674.4 . 46.0
Purity: >98% (HPLC)
Appearance: Crystalline solid.
Solubility: Soluble in water.
InChiKey: MFPHQIYDBUVTRL-HBMYJXICSA-L
SMILES: [Na+].[Na+].NC1=NC2=C(N=CN2C2O[C@H]3CO[P@@]([O-])(=O)OC4C(COP([O-])(=O)OC3C2O)O[C@@H](C4O)N2C=NC3=C(N)N=CN=C23)C(=O)N1
Molecular formula: C20H24N10O13P2 . 2Na
Molecular weight: 674.4 . 46.0
Purity: >98% (HPLC)
Appearance: Crystalline solid.
Solubility: Soluble in water.
InChiKey: MFPHQIYDBUVTRL-HBMYJXICSA-L
SMILES: [Na+].[Na+].NC1=NC2=C(N=CN2C2O[C@H]3CO[P@@]([O-])(=O)OC4C(COP([O-])(=O)OC3C2O)O[C@@H](C4O)N2C=NC3=C(N)N=CN=C23)C(=O)N1
Description:
Potent STING ligand [2-8]. Second messenger in human and mouse cells that triggers interferon production in response to cytosolic DNA [2-4]. Binding to STING leads to activation of IRF3 (IFN regulatory factor 3) and the induction of interferon-beta [3-6]. First cyclic nucleotide in metazoa [4]. Plays a role in bacterial chemotaxis and colonization [1].
Size: 100ug,500ug,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.