DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 53308-83-1
Molecular formula: C7H16N4O2 . CH3COOH
Molecular weight: 188.2 . 60.1
Purity: >99% (TLC)
Appearance: White to off-white solid.
Solubility: Soluble in water, ethanol, methanol or DMSO.
InChiKey: IKPNWIGTWUZCKM-JEDNCBNOBD
SMILES: CC([O-])=O.CNC(=N)NCCC[C@H]([NH3+])C(O)=O
Description:
Endothelium-derived relaxing factor inhibitor. Inhibits the generation of NO from arginine. Competitive, irreversible non-selective inhibitor of all three NOS I, II, and III isoforms (eNOS, iNOS and nNOS). Inhibits the synthesis of nitric oxide (NO) in a dose-dependent and enantiospecific fashion. Useful tool to study the role and the effects of NO in cardiovascular and gastrointestinal disorders, hypertension, diabetes, septic shock, inflammation, infection, stroke and neurodegenerative disorders.