DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 918505-84-7
Molecular formula: C17H14ClF2N3O3S
Molecular weight: 413.8
Purity: >99% (HPLC)
Appearance: Off-white solid.
Solubility: Soluble in DMSO or ethanol.
InChiKey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
SMILES: CCCS(=O)(=O)NC1=CC=C(F)C(C(=O)C2=CNC3=NC=C(Cl)C=C23)=C1F
Description:
Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines.