bs-75482C

DATASHEET

Formulation Powder

Storage: Stable for 2 years after receipt when stored at +4°C. Stock solutions are stable for 3 months when stored at -20°C.

Product Information:

CAS Number: 155141-29-0

Molecular formula: C18H19N3O3S . C4H4O4

Molecular weight: 357.4 . 116.1

Purity: >98% (NMR)

Appearance: White to off-white powder.

Solubility: Soluble in ethanol or buffered aqueous solutions with pH 2.3.

InChiKey: SUFUKZSWUHZXAV-BTJKTKAUSA-N

SMILES: OC(=O)\C=C/C([O-])=O.C[NH+](CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1

Description:

Antidiabetic, hypoglycemic agent [1, 5]. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist [2, 3]. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance [4-6, 8]. Improves blood pressure and vascular function [7]. Enhances proliferation of endogenous neural progenitor cells (NPCs) [9]. Anti-inflammatory compound [10, 11]. Has controversial therapeutic effects on the cardiovascular system [12]. Promotes adipocyte differentiation of mesenchymal stem cells (MSCs) [13].