DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Product Information:
CAS Number: 172889-26-8
Molecular formula: C16H19N5
Molecular weight: 281.4
Purity: >98% (HPLC)
Appearance: White solid.
Solubility: Soluble in DMSO. Slightly soluble in ethanol.
InChiKey: ZVPDNRVYHLRXLX-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)C1=NN(C2=C1C(N)=NC=N2)C(C)(C)C
Description:
Highly potent and selective Scr family tyrosine kinase inhibitor [1, 2, 6, 9]. Shows anti-Ras cancer potential by blocking Ras-induced activation of PAK1 [4]. Antitumor compound [3, 4, 5, 7]. RIP2 inhibitor [9]. Blocks TGF-beta-mediated cellular responses [8, 10].