bs-75452C
[Life Science]
IHR-NAc
DATASHEET
Formulation Solid
Storage: Stable for 1 year after receipt when stored at -20°C.
Product Information:
CAS Number: n.d.
Molecular formula: C22H16Cl3N3O3
Molecular weight: 476.7
Purity: >98% (NMR)
Appearance: White to grey solid.
Solubility: Soluble in DMSO.
InChiKey: KEKPTYABAFCFOT-UHFFFAOYSA-N
SMILES: CC(=O)NC1=CC=C(Cl)C(=C1)C(=O)NC1=CC=C(NC(=O)C2=C(Cl)C=CC(Cl)=C2)C=C1
Molecular formula: C22H16Cl3N3O3
Molecular weight: 476.7
Purity: >98% (NMR)
Appearance: White to grey solid.
Solubility: Soluble in DMSO.
InChiKey: KEKPTYABAFCFOT-UHFFFAOYSA-N
SMILES: CC(=O)NC1=CC=C(Cl)C(=C1)C(=O)NC1=CC=C(NC(=O)C2=C(Cl)C=CC(Cl)=C2)C=C1
Description:
Sonic hedgehog (Shh) signaling pathway inhibitor. Potential anticancer compound. Cell membrane permeable Smoothened (Smo) antagonist. Acts on extra- and intracellular exposed Smo. Binds to the seven-transmembrane (7TM) pocket. Blocks hedgehog-induced movement of Smo into the primary cilium, disengages Smo-dependent abrogation of Gli2 and Gli3 proteolytic processing and inhibits Gli activity induced by loss of PTCH1.
Size: 1mg,5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.