DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Product Information:
CAS Number: 1148118-92-6
Molecular formula: C15H11NO3
Molecular weight: 253.3
Purity: >98% (HPLC, NMR)
Appearance: Yellow solid.
Solubility: Soluble in DMSO (at least 10 mg/ml).
InChiKey: OMKSBDLWMROKNU-WQLSENKSSA-N
SMILES: OC1=CC=C(O)C(\C=C2/C(=O)NC3=C2C=CC=C3)=C1
Description:
Specific non-ATP competitive Aurora A kinase inhibitor [1]. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase [1].