bs-75437C [Life Science]
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Formulation Solid

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 28822-58-4

Molecular formula: C10H14N4O2

Molecular weight: 222.3

Purity: >99% (HPLC)

Appearance: White to off-white solid.

Solubility: Soluble in DMSO, ethanol or methanol. Insoluble in water.

InChiKey: APIXJSLKIYYUKG-UHFFFAOYSA-N

SMILES: CC(C)CN1C2=C(NC=N2)C(=O)N(C)C1=O

Description:

Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor [1, 5, 6, 11]. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis [9]. Enhances differentiation of 3T3-L1 cells [3]. Non-selective adenosine receptor antagonist [4]. Inhibits Ca2+ ion channels [7, 8]. Activates TNF-alpha [10]. Adipogenic [10]. Activates leukotriene synthesis [12]. Reduces inflammation and innate immunity [12].

Size: , 1g,500mg , 1g,500mg

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.