DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Product Information:
CAS Number: 328968-36-1
Molecular formula: C24H19N3O6
Molecular weight: 445.4
Purity: >98% (NMR)
Appearance: Red solid.
Solubility: Soluble in DMSO (10mg/ml).
InChiKey: HEKJYZZSCQBJGB-XDHOZWIPSA-N
SMILES: CC1=NN(C(=O)\C1=C\C1=CC=C(O1)C1=CC(C)=C(C)C=C1[N+]([O-])=O)C1=CC=C(C=C1)C(O)=O
Description:
Reversible cell permeable p300/CBP histone acetyltransferase (HAT) inhibitor. Specific inhibition to p300 (86%) compared to N-acetyltransferase, PCAF, GCN5, Rtt109, Sas or MOZ histone acetyltransferases (<10%). Cell growth inhibitor in melanoma and non-small-cell-lung (NSCL) human cancer cell lines.