bs-75430C
[Life Science]
SMI-4a
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 327033-36-3
Molecular formula: C11H6F3NO2S
Molecular weight: 273.2
Purity: >95% (NMR)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO (at least 5 mg/ml).
InChiKey: NGJLOFCOEOHFKQ-YVMONPNESA-N
SMILES: FC(F)(F)C1=CC(\C=C2/SC(=O)NC2=O)=CC=C1
Molecular formula: C11H6F3NO2S
Molecular weight: 273.2
Purity: >95% (NMR)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO (at least 5 mg/ml).
InChiKey: NGJLOFCOEOHFKQ-YVMONPNESA-N
SMILES: FC(F)(F)C1=CC(\C=C2/SC(=O)NC2=O)=CC=C1
Description:
Selective inhibitor of Pim-1 and Pim-2 protein kinases [1-5]. Inducer of G1 phase cell cycle arrest [1-5]. Inducer of p27Kip1 [1-5]. Inducer of apoptosis through the mitochondrial pathway [1-5]. Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway [1-5]. Downregulates c-myc [1-5]. Inhibitor of PRAS40 phosphorylation and mTOR activity [1-5]. Potential anti-cancer compound [2,4,5]. Blocks prostate cancer growth [2,4,5]. Suppressor of cytokines production in lipopolysaccharide (LPS)-induced acute lung injury (ALI)
Size: 5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.