DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 41443-28-1
Molecular formula: C9H5N3O2
Molecular weight: 187.2
Purity: >98% (HPLC)
Appearance: White to pale yellow solid.
Solubility: Soluble in DMSO (at least 5 mg/ml), ethyl acetate or 100% ethanol (1.2 mg/ml); insoluble in water.
InChiKey: LZMHWZHOZLVYDL-UHFFFAOYSA-N
SMILES: O=C1ON=C2C=NC3=CC=CC=C3N12
Description:
Potent and highly selective, irreversible inhibitor of soluble guanylyl cyclase (sGC). The binding is competitive with nitric oxide (NO) [1-5]. Tool to elucidate the nitric oxide (NO)-cGMP pathway [1-5]. Apoptosis inhibitor [6] Inhibits growth and migration of prostate cancer cells independent of its effects on GMP levels [6].