bs-75416C [Life Science]
KBU2046
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Formulation Solid

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 1143863-69-7

Molecular formula: C15H11FO2

Molecular weight: 242.2

Purity: >98% (HPLC)

Appearance: White to off-white solid.

Solubility: Soluble in DMSO, ethanol, methanol or DCM. Insoluble in water.

InChiKey: XKAFGKFIJBGYAP-UHFFFAOYSA-N

SMILES: O=C1C(C2=CC=C(F)C=C2)COC3=CC=CC=C31

Description:

Highly selective metastasis inhibitor in vitro. Binds to and stabilizes Cdc37-HSP90beta heterocomplexes, consequently blocking its function and inhibiting cancer cell motility. Does not bind to Cdc37 or HSP90beta alone. Inhibits cancer metastasis in vivo in murine models of human prostate and breast cancer. Shown to exhibit a complete lack of cellular cytotoxicity and systemic toxicity.

Size: 1mg,5mg,25mg,

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.