DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 170632-47-0
Molecular formula: C19H16N2O2
Molecular weight: 304.4
Purity: >98% (HPLC)
Appearance: White to pale yellow powder.
Solubility: Soluble in DMSO, methanol or dichloromethane.
InChiKey: OQQVFCKUDYMWGV-UHFFFAOYSA-N
SMILES: OCC1=CC=C(O1)C1=NN(CC2=CC=CC=C2)C2=CC=CC=C12
Description:
Nitric oxide (NO) independent, superoxide-sensitive soluble guanylyl cyclase (sGC) activator [1, 4]. Induces concentration-dependent increase in cGMP levels [1, 4]. Inhibits platelet adhesion to collagen [2, 8]. Thombosis inhibitor [3]. Non-specific phosphodiesterase inhibitor [5]. Na+ channel blocker [6, 9]. Anticancer compound [7, 8]. HIF-alpha inhibitor [7, 10]. Blocks angiogenesis. Tumor growth inhibitor [7, 10]. Apoptosis inducer [11]. NK cell differentiation enhancer [12]. TRAIL sensitizer [13].