DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Product Information:
CAS Number: 167869-21-8
Molecular formula: C16H13NO3
Molecular weight: 267.3
Purity: >98% (NMR)
Appearance: Yellow solid.
Solubility: Soluble in anhydrous DMSO, methanol or dichloromethane. Slightly soluble in ethanol.
InChiKey: QFWCYNPOPKQOKV-UHFFFAOYSA-N
SMILES: COC1=C(N)C(=CC=C1)C1=CC(=O)C2=CC=CC=C2O1
Description:
Highly selective, reversible and cell permeable MEK (MAP kinase kinase) inhibitor [1-3, 7]. Blocks the phosphorylation and activation of the MAP kinase pathway [1-3, 7]. T cell activation inhibitor [4]. Inhibits cell growth and cell proliferation of several cancer cells [5, 6, 8].