bs-75403C
[Life Science]
Bisindolylmaleimide VIII . AcOH [Ro 31-7549]
DATASHEET
Formulation Powder
Storage: Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Product Information:
CAS Number: 138516-31-1
Molecular formula: C24H22N4O2 . CH3COOH
Molecular weight: 398.5 . 60.1
Purity: >98% (NMR)
Appearance: Red powder.
Solubility: Soluble in DMSO, methanol or water. Slightly soluble in ethanol.
InChiKey: VEOXVBTXROWDAH-UHFFFAOYSA-N
SMILES: CC(O)=O.CN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CN(CCCN)C2=C1C=CC=C2
Molecular formula: C24H22N4O2 . CH3COOH
Molecular weight: 398.5 . 60.1
Purity: >98% (NMR)
Appearance: Red powder.
Solubility: Soluble in DMSO, methanol or water. Slightly soluble in ethanol.
InChiKey: VEOXVBTXROWDAH-UHFFFAOYSA-N
SMILES: CC(O)=O.CN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CN(CCCN)C2=C1C=CC=C2
Description:
Selective protein kinase C (PKC) inhibitor [1-3]. Inhibits proliferation of cultured mouse epidermal keratinocytes [4]. Enhances Fas- and TRAIL-mediated apoptosis [5, 6]. Inhibits T cell-mediated autoimmune diseases [5]. Inhibits stimulation of insulin secretion by glucose [8]. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2) [7].
Size: 1mg,5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.