bs-75400C
[Life Science]
Bisindolylmaleimide IX . methansulfonate [Ro 31-8220]
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Product Information:
CAS Number: 138489-18-6
Molecular formula: C25H23N5O2S . CH4O3S
Molecular weight: 457.6 . 96.1
Purity: >98% (NMR)
Appearance: Red solid.
Solubility: Soluble in DMSO.
InChiKey: SAWVGDJBSPLRRB-UHFFFAOYSA-N
SMILES: CS(O)(=O)=O.CN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CN(CCCSC(N)=N)C2=C1C=CC=C2
Molecular formula: C25H23N5O2S . CH4O3S
Molecular weight: 457.6 . 96.1
Purity: >98% (NMR)
Appearance: Red solid.
Solubility: Soluble in DMSO.
InChiKey: SAWVGDJBSPLRRB-UHFFFAOYSA-N
SMILES: CS(O)(=O)=O.CN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CN(CCCSC(N)=N)C2=C1C=CC=C2
Description:
Selective and cell permeable protein kinase C (PKC) inhibitor [1, 2, 3]. Inhibits the stimulation of insulin secretion by glucose [4, 11]. Inhibits T cell activation [5]. Apoptosis inducer [6, 8, 9,10, 13]. Potent glycogen synthase kinase-3 (GSK-3) inhibitor [7]. Transcription inhibitor [9]. Induces TNF receptor family-mediated cell death [10]. Pim-1 kinase inhibitor [12]. Antitumor compound [13].
Size: 1mg,5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.