bs-75397C [Life Science]
LY-294,002
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DATASHEET

Formulation Solid

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 154447-36-6

Molecular formula: C19H17NO3

Molecular weight: 307.4

Purity: >99% (NMR)

Appearance: White to off-white crystalline solid.

Solubility: Soluble in DMSO, 100% ethanol or methanol.

InChiKey: CZQHHVNHHHRRDU-UHFFFAOYSA-N

SMILES: O=C1C=C(OC2=C(C=CC=C12)C1=CC=CC=C1)N1CCOCC1

Description:

Potent, cell permeable, highly specific, reversible PI(3)K (phosphoinositide 3-kinase) inhibitor. pan-class I / II / III PI3K inhibitor. Acts on the ATP-binding site of the enzyme. In solution more stable than wortmannin. Antagonizes P-glycoprotein-mediated multidrug resistance. Blocks Akt phosphorylation. Pim-1 kinase inhibitor. Autophagy inhibitor (autophagosome formation). Inhibitor of BET bromodomain proteins BRD2, BRD3 and BRD4.

Size: 1mg,5mg,25mg,

Applications: Life Science()

For research use only. Not intended for diagnostic or therapeutic use.