bs-75394C
[Life Science]
LY-333,531 . hydrochloride
DATASHEET
Formulation Solid
Storage: Stable for 1 year after receipt when stored at -20°C.
Product Information:
CAS Number: 169939-93-9
Molecular formula: C28H28N4O3 . HCl
Molecular weight: 468.6 . 36.5
Purity: >98% (HPLC)
Appearance: Red solid.
Solubility: Soluble in DMSO. Slightly soluble in 100% ethanol or water.
InChiKey: NYQIEYDJYFVLPO-FERBBOLQSA-N
SMILES: Cl.CN(C)C[C@@H]1CCN2C=C(C3=C2C=CC=C3)C2=C(C(=O)NC2=O)C2=CN(CCO1)C1=C2C=CC=C1
Molecular formula: C28H28N4O3 . HCl
Molecular weight: 468.6 . 36.5
Purity: >98% (HPLC)
Appearance: Red solid.
Solubility: Soluble in DMSO. Slightly soluble in 100% ethanol or water.
InChiKey: NYQIEYDJYFVLPO-FERBBOLQSA-N
SMILES: Cl.CN(C)C[C@@H]1CCN2C=C(C3=C2C=CC=C3)C2=C(C(=O)NC2=O)C2=CN(CCO1)C1=C2C=CC=C1
Description:
Isozyme selective inhibitor of protein kinase Cbeta (PKCbeta) [1, 6, 10, 11, 13]. PKCbetaI and PKCbetaII isozyme inhibitor [2-3, 6, 10, 11, 13]. Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy [1, 3, 5-7, 9-11]. Anti-cancer and anti-angiogenic compound [4-5, 8]. Suppresses glucose-induced adhesion of human monocytes to endothelial cells [12]. Suppresses ERK1/2 and Akt phosphorylation [14].
Size: 1mg,5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.