DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 111025-46-8
Molecular formula: C19H20N2O3S
Molecular weight: 356.4
Purity: >98% (HPLC)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO (2.5 mg/ml) or dimethylformamide (DMF) (2.5 mg/ml).
InChiKey: HYAFETHFCAUJAY-UHFFFAOYSA-N
SMILES: CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
Description:
Thiazolidinedione (TZD) reference compound [2, 3]. Selective PPARgamma agonist. Selectively activates PPARgamma-1 [1, 3]. Anti-diabetic [3-5], decreasing insulin resistance in adipose tissue. Is about one tenth as potent as rosiglitazone [1, 2]. Lipid metabolism modulator [6]. Estrogen synthesis inhibitor [7]. NF-kappaB inhibitor [8]. Neuroprotective [9].