DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 667463-62-9
Molecular formula: C16H10BrN3O2
Molecular weight: 356.2
Purity: >98% (NMR)
Appearance: Dark red solid.
Solubility: Soluble in DMSO.
InChiKey: DDLZLOKCJHBUHD-WAVHTBQISA-N
SMILES: O\N=C1\C(\NC2=CC=CC=C\12)=C1\C(=O)NC2=C1C=CC(Br)=C2
Description:
Phosphoinositide-dependent kinase 1 (PDK1) inhibitor. Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor. JAK/STAT3 signaling inhibitor. Apoptosis inducer. Potent antiproliferative agent in malignant lymphoid cell. Antimetastatic agent. Potent chemosensitizing agent fighting TRAIL resistant cancer cells.