bs-75370C
[Life Science]
Alsterpaullone
DATASHEET
Formulation Powder
Storage: Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 237430-03-4
Molecular formula: C16H11N3O3
Molecular weight: 293.3
Purity: >98% (NMR)
Appearance: Yellow to brown powder.
Solubility: Soluble in DMSO; insoluble in water or 100% ethanol.
InChiKey: OLUKILHGKRVDCT-UHFFFAOYSA-N
SMILES: [O-][N+](=O)C1=CC2=C(NC3=C2CC(=O)NC2=C3C=CC=C2)C=C1
Molecular formula: C16H11N3O3
Molecular weight: 293.3
Purity: >98% (NMR)
Appearance: Yellow to brown powder.
Solubility: Soluble in DMSO; insoluble in water or 100% ethanol.
InChiKey: OLUKILHGKRVDCT-UHFFFAOYSA-N
SMILES: [O-][N+](=O)C1=CC2=C(NC3=C2CC(=O)NC2=C3C=CC=C2)C=C1
Description:
Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor [1]. Anti-tumor compound [1] Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM) [2, 4]. GSK-3beta (glycogen synthase kinase-3beta) inhibitor [2, 3]. Apoptosis inhibitor [6, 7]. Apoptosis inducer [5]. Angiogenesis inhibitor [8].
Size: 1mg,5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.