bs-75364C
[Life Science]
SB203580
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 152121-47-6
Molecular formula: C21H16FN3OS
Molecular weight: 377.4
Purity: >99% (HPLC)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO or methanol.
InChiKey: CDMGBJANTYXAIV-UHFFFAOYSA-N
SMILES: C[S+]([O-])C1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=NC=C1)C1=CC=C(F)C=C1
Molecular formula: C21H16FN3OS
Molecular weight: 377.4
Purity: >99% (HPLC)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO or methanol.
InChiKey: CDMGBJANTYXAIV-UHFFFAOYSA-N
SMILES: C[S+]([O-])C1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=NC=C1)C1=CC=C(F)C=C1
Description:
Cell permeable, specific p38 MAP kinase inhibitor [1, 2, 5]. Binds to the ATP binding site of p38 MAP kinase [3]. T cell proliferation inhibitor [4]. IL-2 production inhibitor [4]. SAPK/JNK inhibitor [5]. COX-1 and -2 inhibitor [6]. Raf-1 activator [7, 8]. Apoptosis enhancer [9]. Antiproliferative [10]. PDK1 inhibitor [10]. Anti-inflammatory [11]. Review [12]. Enhances cardiomyogenesis of human embryonic stem cells (hESCs) [13].
Size: 1mg,5mg,25mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.