DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 152121-30-7
Molecular formula: C20H14FN3O
Molecular weight: 331.3
Purity: >97% (HPLC)
Appearance: Off-white solid.
Solubility: Soluble in methanol, DMSO or acetone; slightly soluble in ethyl acetate.
InChiKey: QHKYPYXTTXKZST-UHFFFAOYSA-N
SMILES: OC1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=NC=C1)C1=CC=C(F)C=C1
Description:
Potent and cell permeable p38 MAP kinase inhibitor [1, 2]. Apoptosis inducer [3]. Inhibits p38alpha and beta, but not gamma and delta isoforms [4, 5]. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators [6]. JNK activator [7]. Autophagic vacuole inducer [8]