bs-75354C
[Life Science]
NU6102
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 444722-95-6
Molecular formula: C18H22N6O3S
Molecular weight: 402.5
Purity: >98% (NMR)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO.
InChiKey: OWXORKPNCHJYOF-UHFFFAOYSA-N
SMILES: NS(=O)(=O)C1=CC=C(NC2=NC3=C(N=CN3)C(OCC3CCCCC3)=N2)C=C1
Molecular formula: C18H22N6O3S
Molecular weight: 402.5
Purity: >98% (NMR)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO.
InChiKey: OWXORKPNCHJYOF-UHFFFAOYSA-N
SMILES: NS(=O)(=O)C1=CC=C(NC2=NC3=C(N=CN3)C(OCC3CCCCC3)=N2)C=C1
Description:
Potent CDK1/cyclin B (IC50 = 9.5 nM) and CDK2/cyclin A3 (IC50 = 5.4 nM) inhibitor [1-3]. 1'000-fold more potent than NU2058 [1]. Selective for CDK1 and CDK2 compared to CDK4/D1 (IC50 = 1.6 µM), DYRK1A (IC50 = 0.9 µM), PDK1 (IC50 = 0.8 µM) and ROCK-II (IC50 = 0.6 µM) [1]. Inhibits cell growth [1].
Size: 1mg,5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.