bs-75353C
[Life Science]
Nocodazole
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 31430-18-9
Molecular formula: C14H11N3O3S
Molecular weight: 301.3
Purity: >98% (NMR)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO or dimethylformamide; almost insoluble in water.
InChiKey: KYRVNWMVYQXFEU-UHFFFAOYSA-N
SMILES: COC(=O)NC1=NC2=CC=C(C=C2N1)C(=O)C1=CC=CS1
Molecular formula: C14H11N3O3S
Molecular weight: 301.3
Purity: >98% (NMR)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO or dimethylformamide; almost insoluble in water.
InChiKey: KYRVNWMVYQXFEU-UHFFFAOYSA-N
SMILES: COC(=O)NC1=NC2=CC=C(C=C2N1)C(=O)C1=CC=CS1
Description:
Microtubule inhibitor [1, 2, 4]. Antitumor compound [1, 2]. Mitosis inhibitor [3]. Arrests the cell cycle at G2/M phase [9]. Promotes tubulin depolymerization [4]. Induces fragmentation of the Golgi complex [5]. Inhibits the T cell antigen receptor [6]. Stimulates the intrinsic GTPase activity of tubulin [7]. Activates the JNK/SAPK signaling pathway [8]. Apoptosis inducer [10, 11]. Autophagy inhibition through prevention of autophagosome-lysosome fusion.
Size: 5mg,10mg,25mg,50mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.