bs-75338C
[Life Science]
H-89 . dihydrochloride
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at +4°C.
Product Information:
CAS Number: 130964-39-5; 127243-85-0 (free base)
Molecular formula: C20H20BrN3O2S . 2HCl
Molecular weight: 446.4 . 72.9
Purity: >98% (NMR)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO (50mg/ml), DMF (20mg/ml), ethanol (1mg/ml) or methanol (1mg/ml). Slightly soluble in water.
InChiKey: ZKZXNDJNWUTGDK-NSCUHMNNSA-N
SMILES: BrC1=CC=C(C=CCNCCNS(=O)(=O)C2=C3C=CN=CC3=CC=C2)C=C1
Molecular formula: C20H20BrN3O2S . 2HCl
Molecular weight: 446.4 . 72.9
Purity: >98% (NMR)
Appearance: White to off-white solid.
Solubility: Soluble in DMSO (50mg/ml), DMF (20mg/ml), ethanol (1mg/ml) or methanol (1mg/ml). Slightly soluble in water.
InChiKey: ZKZXNDJNWUTGDK-NSCUHMNNSA-N
SMILES: BrC1=CC=C(C=CCNCCNS(=O)(=O)C2=C3C=CN=CC3=CC=C2)C=C1
Description:
Cell permeable potent and selective cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor [1-3]. Protein kinase Cµ (PKCµ) inhibitor [4]. Ca2+/calmodulin-dependent protein kinase II inhibitor [2]. Casein kinase I inhibitor [2]. Myosin light chain kinase (MLCK) inhibitor [2]. Apoptosis enhancer [5]. Tool to study protein crystal structure-inhibitor interactions [6]. Rho kinase inhibitor [7]. Cell proliferation inhibitor [8]. Review [9].
Size: 1mg,5mg,25mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.