DATASHEET
Formulation
Powder
Storage:
Stable for 1 year after receipt when stored at -20°C.
Product Information:
CAS Number: 1104011-59-7
Molecular formula: C32H37N5O6
Molecular weight: 587.7
Purity: >98% (HPLC)
Appearance: Lyophilized powder.
Solubility: Soluble in DMSO.
InChiKey: PIJMRHCPKXLMIS-DOYMOWJKSA-N
SMILES: CC(C1=CC=C(C=C1O2)NC([C@H](C)NC([C@H](CC(C)C)NC([C@@H](NC(C)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=CC2=O
Description:
Fluorogenic peptide substrate for measuring chymotrypsin-like activity of the 20S proteasome. This substrate is hydrolyzed by the beta5-subunit of the 20S proteasome to generate detectable fluorescence. 20S Proteasome enzyme requires activation with 0.035% SDS in the assay buffer. Excitation: 345nm. Emission: 445nm. Specific substrate to the constitutive proteasome, not hydrolyzed efficiently by the immunoproteasome. This substrate is useful for inhibitor screening and kinetic analysis.