bs-75316C
[Life Science]
MOTS-c (K14Q Mutant) (human)
DATASHEET
Formulation Powder
Storage: Stable for 1 year after receipt when stored at -20°C.
Product Information:
CAS Number: n.d.
Molecular formula: C100H148N28O23S2 . C2HF3O2
Molecular weight: 2174.6 . 114.0
Purity: >95% (HPLC)
Appearance: Solid lyophilized powder.
Solubility: Soluble in water.
InChiKey: DXUYVBXOAGWAKV-JBICZICZSA-N
SMILES: [H]N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)CC2=CC=C(O)C=C2)=O)CC3=CC=CC=C3)=O)[C@@H](C)CC)=O)CC4=CC=C(O)C=C4)=O)=O)CCSC)=O)=O)=O)CC5=CNC6=C5C=CC=C6)=O)=O)CCSC.O=C(O)C(F)(F)F
Molecular formula: C100H148N28O23S2 . C2HF3O2
Molecular weight: 2174.6 . 114.0
Purity: >95% (HPLC)
Appearance: Solid lyophilized powder.
Solubility: Soluble in water.
InChiKey: DXUYVBXOAGWAKV-JBICZICZSA-N
SMILES: [H]N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)CC2=CC=C(O)C=C2)=O)CC3=CC=CC=C3)=O)[C@@H](C)CC)=O)CC4=CC=C(O)C=C4)=O)=O)CCSC)=O)=O)=O)CC5=CNC6=C5C=CC=C6)=O)=O)CCSC.O=C(O)C(F)(F)F
Description:
The mitochondria-derived peptide (MDP) MOTS-c promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK). It induces cellular and systemic glucose uptake and improves insulin sensitivity and has been shown to prevent diet-induced obesity (DIO) in mice. This K14Q mutant of MOTS-c has been shown to be associated with exceptional longevity and may be interesting for aging research.
Size: 1mg,5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.