DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 133407-86-0
Molecular formula: C25H39N3O5
Molecular weight: 461.6
Purity: >95% (HPLC)
Appearance: Solid lyophilized powder.
Solubility: Soluble in DMSO.
InChiKey: QEJRGURBLQWEOU-FKBYEOEOSA-N
SMILES: [H]C(=O)[C@H](CCC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1
Description:
Potent, reversible and cell permeable proteasome inhibitor. Specifically inhibits the chymotrypsin-like activity of the proteasome. Calpain and cathepsin inhibitor. Apoptosis inducer in Rat-1 and PC12 cells via a p53-dependent pathway. Autophagy activator.