bs-75292C
[Life Science]
Q-VD-OPh
DATASHEET
Formulation Solid
Storage: Stable for 3 years after receipt when stored at -20°C.
Product Information:
CAS Number: 1135695-98-5 (anhydrous)
Molecular formula: C26H25F2N3O6
Molecular weight: 513.5
Purity: >95% (TLC)
Appearance: White solid.
Solubility: Soluble in DMSO.
InChiKey: OOBJCYKITXPCNS-AKRCKQFNSA-N
SMILES: CC(C)[C@H](NC(=O)C1=CC=C2C=CC=CC2=N1)C(=O)NC(CC(O)=O)C(=O)COC1=C(F)C=CC=C1F
Molecular formula: C26H25F2N3O6
Molecular weight: 513.5
Purity: >95% (TLC)
Appearance: White solid.
Solubility: Soluble in DMSO.
InChiKey: OOBJCYKITXPCNS-AKRCKQFNSA-N
SMILES: CC(C)[C@H](NC(=O)C1=CC=C2C=CC=CC2=N1)C(=O)NC(CC(O)=O)C(=O)COC1=C(F)C=CC=C1F
Description:
Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6-difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Used in apoptosis and inflammasome studies.
Size: 1mg,5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.