bs-75290C
[Life Science]
Pam3Cys-Ser-(Lys)4 . trihydrochloride
DATASHEET
Formulation Powder
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 112208-04-5; 112208-00-1 (free base)
Molecular formula: C81H156N10O13S . 3HCl
Molecular weight: 1510.3 . 109.4
Purity: Absence of detectable protein or DNA contaminants with agonistic TLR activity.
Appearance: Colorless powder.
Solubility: Soluble in water, saline or aqueous buffers at pH <7.5.
InChiKey: ZRKOETJPZDQIFB-OQOFFOABSA-N
SMILES: CCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)N[C@@H](CO)C(=O)C(=O)[C@H](CCCCN)NN[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O
Molecular formula: C81H156N10O13S . 3HCl
Molecular weight: 1510.3 . 109.4
Purity: Absence of detectable protein or DNA contaminants with agonistic TLR activity.
Appearance: Colorless powder.
Solubility: Soluble in water, saline or aqueous buffers at pH <7.5.
InChiKey: ZRKOETJPZDQIFB-OQOFFOABSA-N
SMILES: CCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)N[C@@H](CO)C(=O)C(=O)[C@H](CCCCN)NN[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O
Description:
Selective agonist of TLR1/TLR2 complex. Cell permeable, water soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Potent and effective immune adjuvant. Exerts strong local response, enhances IgG2a and IgG1 titers and upregulates proinflammatory and Th1 cytokine genes. Potent activator of the proinflammatory transcription factor NF-kappaB.
Size: 2mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.