bs-75288C
[Life Science]
BQ-123 . sodium salt
DATASHEET
Formulation Solid
Storage: Stable for 3 years after receipt when stored at -20°C.
Product Information:
CAS Number: 136655-57-7; 136553-81-6 (free base)
Molecular formula: C31H42N6O7 . Na
Molecular weight: 609.7 . 23.0
Purity: >98% (HPLC)
Appearance: White solid.
Solubility: Soluble in water.
InChiKey: FLIKEIGEOXCRRG-DRBUQPBJSA-M
SMILES: [Na+].CC(C)CC1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC([O-])=O)NC(=O)[C@@H](CC2=CNC3=C2C=CC=C3)NC1=O)C(C)C
Molecular formula: C31H42N6O7 . Na
Molecular weight: 609.7 . 23.0
Purity: >98% (HPLC)
Appearance: White solid.
Solubility: Soluble in water.
InChiKey: FLIKEIGEOXCRRG-DRBUQPBJSA-M
SMILES: [Na+].CC(C)CC1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC([O-])=O)NC(=O)[C@@H](CC2=CNC3=C2C=CC=C3)NC1=O)C(C)C
Description:
Potent and selective endothelin receptor A (ETA) antagonist [1-3]. Suppresses the ET-1-induced decrease of LPL activity [4]. Shows protective effects in ischemic acute renal failure [5]. Neuroprotective [6, 10]. Anti-hypertensive [7]. Inhibits ET-1 receptor binding and blocks Ca2+ mobilization, cellular contraction and MAP kinase activation [8]. Cardiovascular agent [9]. Reduces myocardial infarct size and oxidant injury [11]. Selected Reviews [12, 13].
Size: 1mg,5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.