bs-75285C
[Life Science]
Daptomycin
DATASHEET
Formulation Powder
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 103060-53-3
Molecular formula: C72H101N17O26
Molecular weight: 1620.7
Purity: >95% (HPLC)
Appearance: Off-white to pale yellow powder.
Solubility: Soluble in water (25mg/ml), DMSO (50mg/ml) or methanol (5mg/ml).
InChiKey: DOAKLVKFURWEDJ-RWDRXURGSA-N
SMILES: O=C(O[C@H](C)[C@H](NC([C@H](CC(O)=O)NC([C@@H](NC([C@@H](NC(CCCCCCCCC)=O)CC1=CNC2=C1C=CC=C2)=O)CC(N)=O)=O)=O)C(NC3)=O)[C@H](CC(C4=C(N)C=CC=C4)=O)NC([C@@H](NC([C@@H](CO)NC(CNC([C@H](CC(O)=O)NC([C@@H](C)NC([C@H](CC(O)=O)NC([C@@H](NC3=O)CCCN)=O)=O)=O)=O)=O)=O)[C@H](C)CC(O)=O)=O
Molecular formula: C72H101N17O26
Molecular weight: 1620.7
Purity: >95% (HPLC)
Appearance: Off-white to pale yellow powder.
Solubility: Soluble in water (25mg/ml), DMSO (50mg/ml) or methanol (5mg/ml).
InChiKey: DOAKLVKFURWEDJ-RWDRXURGSA-N
SMILES: O=C(O[C@H](C)[C@H](NC([C@H](CC(O)=O)NC([C@@H](NC([C@@H](NC(CCCCCCCCC)=O)CC1=CNC2=C1C=CC=C2)=O)CC(N)=O)=O)=O)C(NC3)=O)[C@H](CC(C4=C(N)C=CC=C4)=O)NC([C@@H](NC([C@@H](CO)NC(CNC([C@H](CC(O)=O)NC([C@@H](C)NC([C@H](CC(O)=O)NC([C@@H](NC3=O)CCCN)=O)=O)=O)=O)=O)=O)[C@H](C)CC(O)=O)=O
Description:
Daptomycin, a naturally occurring cyclic lipopeptide, is a calcium-dependent antibiotic. It exhibits potent bacteriocidal activity against most Gram-positive bacteria in vitro and in vivo, including antibiotic-resistant strains such as MRSA and VRE. Daptomycin disrupts the bacterial plasma membrane function, which results in membrane depolarization consequently leading to inhibition of protein, DNA and RNA synthesis, essential for cell division and cell wall synthesis.
Size: 25mg,100mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.