bs-75269C
[Life Science]
Trichostatin A (synthetic)
DATASHEET
Formulation Solid
Storage: Stable for 3 years after receipt when stored at -20°C.
Product Information:
CAS Number: 58880-19-6
Molecular formula: C17H22N2O3
Molecular weight: 302.4
Purity: >95% (HPLC)
Appearance: Off-white solid.
Solubility: Soluble in DMSO, ethanol, methanol, dimethyl formamide, acetonitrile or chloroform. Insoluble in water or hexane.
InChiKey: RTKIYFITIVXBLE-QEQCGCAPSA-N
SMILES: C[C@H](\C=C(/C)\C=C\C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
Molecular formula: C17H22N2O3
Molecular weight: 302.4
Purity: >95% (HPLC)
Appearance: Off-white solid.
Solubility: Soluble in DMSO, ethanol, methanol, dimethyl formamide, acetonitrile or chloroform. Insoluble in water or hexane.
InChiKey: RTKIYFITIVXBLE-QEQCGCAPSA-N
SMILES: C[C@H](\C=C(/C)\C=C\C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
Description:
Antibiotic, antifungal and antiprotozoal agent. Potent and reversible, cell permeable inhibitor of class I and II histone deacetylases (HDACs). Anticancer, immunosuppressive, antifibrogenic compound. Induces apoptosis and cell growth arrest at both G1 and G2/M phases. Also inactivates mitotic spindle checkpoint. Enhances the efficacy of anticancer agents that target DNA. Downregulates DNA methyltransferase DNMT1 and affects DNA methylation. Telomerase inhibitor. Smooth muscle cell proliferation inhibitor. Anti-inflammatory and inhibits osteoclastogenesis and bone resorption. Promotes either self-renewal or differentiation of embryonic stem cells.
Size: 1mg,5mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.