DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 107019-95-4
Molecular formula: C11H12BrN5O . H2O
Molecular weight: 310.2 . 18.0
Purity: >97% (HPLC)
Appearance: Amorphous solid.
Solubility: Soluble in DMSO, ethanol or methanol.
InChiKey: KHJREOQCERRAME-OWOJBTEDSA-N
SMILES: O=C(NC/C=C/C1=CN=C(N)N1)C2=CC(Br)=CN2
Description:
Inhibitor of CDK5/p25 (IC50=4µM) and GSK-3beta (IC50=12µM). Potentially useful in neuronal diseases research. Antagonist of serotonergic receptors. Shown to reduce voltage-dependent calcium elevation. Moderate anticancer compound. Inhibits cell growth in a panel of cancer cell lines at low µM range. Antiprotozoal agent. Antibacterial. Plays a role in the sponge antibacterial defense.