bs-75253C
[Life Science]
Secalonic acid F
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 60687-07-2
Molecular formula: C32H30O14
Molecular weight: 638.6
Purity: >95% (HPLC)
Appearance: Yellow solid.
Solubility: Soluble in DMSO, ethanol or methanol.
InChiKey: DRYDKQOPVBDZMQ-WVMRRKDFSA-N
SMILES: OC1=C2[C@](OC3=CC=C(C4=C(O)C(C(C5=C(O)C[C@H](C)[C@H](O)[C@]5(C(OC)=O)O6)=O)=C6C=C4)C(O)=C3C2=O)(C(OC)=O)[C@H](O)[C@@H](C)C1
Molecular formula: C32H30O14
Molecular weight: 638.6
Purity: >95% (HPLC)
Appearance: Yellow solid.
Solubility: Soluble in DMSO, ethanol or methanol.
InChiKey: DRYDKQOPVBDZMQ-WVMRRKDFSA-N
SMILES: OC1=C2[C@](OC3=CC=C(C4=C(O)C(C(C5=C(O)C[C@H](C)[C@H](O)[C@]5(C(OC)=O)O6)=O)=C6C=C4)C(O)=C3C2=O)(C(OC)=O)[C@H](O)[C@@H](C)C1
Description:
Mycotoxin. Common contaminant in corn and other grains. Hybrid dimer of Blennolide A and B. Cytotoxic anticancer compound. Reported to induce apoptosis by modulating RhoGDI 2 levels in HL60 cells. Protein tyrosine phosphatase 1B (PTP1B) inhibitor (IC50=9.6µM). PTP1B is thought to function as a negative regulator of insulin and leptin signal transduction and therefore being involved in type 2 diabetes and obesity pathology. Antimicrobial agent against Bacillus megaterium. Allelopathic agent.
Size: 1mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.