bs-75241C

DATASHEET

Formulation Solid

Storage: Stable for 2 years after receipt when stored at +4°C.

Product Information:

CAS Number: 473-98-3

Molecular formula: C30H50O2

Molecular weight: 442.7

Purity: >98% (NMR)

Appearance: White solid.

Solubility: Soluble in DMSO, DMF or ethanol.

InChiKey: FVWJYYTZTCVBKE-ROUWMTJPSA-N

SMILES: [H][C@]12[C@@H](CC[C@]1(CO)CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(C)=C

Description:

Specific SREBPs (sterol regulatory element-binding proteins) inhibitor. Inhibits ER-Golgi translocation of SREBPs through binding to SCAP in an INSIG-dependent manner. Improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques. Lowers cholesterol levels through inhibition of SREBP-2 activation. Reduces weight gain and adipose tissue size in vivo. Increases oxygen consumption and energy expenditure. Increases UCP1/2 levels in brown adipose tissue (BAT) after cold stimulation. Anticancer compound. Apoptosis inducer. DNA topoisomerase II inhibitor. Anti-inflammatory compound. Shown to inhibit LPS-induced NO production through the TLR4/NF-kappaB signaling pathway. Antiviral compound.