DATASHEET
Formulation
Solid
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 1381782-08-6
Molecular formula: C34H30O14
Molecular weight: 662.6
Purity: >98% (HPLC)
Appearance: Solid.
Solubility: Soluble in DMSO or ethanol.
InChiKey: GMCZVCXZGZGZPX-HOTGVXAUSA-N
SMILES: COC(=O)C[C@@H]1CC2=CC3=C(C(O)=CC(OC)=C3C3=C4C=C5C[C@@H](CC(=O)OC)OC(=O)C5=C(O)C4=C(O)C=C3OC)C(O)=C2C(=O)O1
Description:
Antibiotic. Exhibits broad activity against Gram-positive bacteria. Bacterial cell division protein FtsZ inhibitor (IC50=8.2µg/ml). Inhibits the GTPase activity of FtsZ in vitro (IC50=7.0µg/ml). Induces apoptosis and autophagy and inhibits cell growth at G2/M in human prostate cancer cells. Activates ATP hydrolysis and induces calcium sensitized swelling of rat liver mitochondria.