bs-75230C

DATASHEET

Formulation Solid

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 78916-42-4 and 1174387-94-0

Molecular formula: C26H32O4

Molecular weight: 408.5

Purity: >97% (HPLC)

Appearance: Solid.

Solubility: Soluble in DMSO, ethanol or methanol. Insoluble in water.

InChiKey: DKNIJLWIVUCTHW-CPNJWEJPSA-N

SMILES: COC1=C(C\C=C(/C)CCC=C(C)C)C(O)=C(C(O)=O)C(CCC2=CC=CC=C2)=C1

Description:

Antidiabetic agent. Potent and selective partial agonist of peroxisome proliferator-activated receptor gamma (PPARgamma), a nuclear receptor regulating lipid and glucose metabolism. Has low nanomolar binding affinity to PPARgamma and micromolar binding to the isotypes PPARalpha and PPARbeta/delta. The binding affinity constant to PPARgamma is 12 times lower than Amorfrutin A (Prod. No. bs-75228C). Glucose-lowering agent. Improves insulin sensitivity, glucose tolerance and blood lipid variables without increase of fat storage or hepatoxicity. Shows potent PPARgamma-dependent anti-inflammatory activity. Antimicrobial agent.