bs-75226C
[Life Science]
Celastrol
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 34157-83-0
Molecular formula: C29H38O4
Molecular weight: 450.6
Purity: >98% (HPLC)
Appearance: Red solid.
Solubility: Soluble in DMSO, ethanol or dimethylformamide. Insoluble in water.
InChiKey: KQJSQWZMSAGSHN-JJWQIEBTSA-N
SMILES: [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(O)=O
Molecular formula: C29H38O4
Molecular weight: 450.6
Purity: >98% (HPLC)
Appearance: Red solid.
Solubility: Soluble in DMSO, ethanol or dimethylformamide. Insoluble in water.
InChiKey: KQJSQWZMSAGSHN-JJWQIEBTSA-N
SMILES: [H][C@@]12C[C@@](C)(CC[C@]1(C)CC[C@]1(C)C3=CC=C4C(C)=C(O)C(=O)C=C4[C@]3(C)CC[C@@]21C)C(O)=O
Description:
Anti-obesity agent. Potent leptin sensitizer. Antioxidant. Potent lipid peroxidation inhibitor. NADPH oxidases (NOX1, 2, 4 and 5) inhibitor. Anti-inflammatory. NF-kappaB inhibitor. HSP90 inhibitor and HSP70 inducer. Anticancer agent. Apoptosis and autophagy inducer. Inhibits PI3K/Akt signaling pathways. Anti-metastatic and anti-angiogenic compound. Reduces VEGFR expression and inhibits HIF-1alpha pathway. Topoisomerase II inhibitor. 20S proteasome chymotrypsin-like activity inhibitor. Potential antiviral and anti-Alzheimer's agent.
Size: 5mg,10mg,50mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.