DATASHEET
Formulation
Powder
Storage:
Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 22368-21-4
Molecular formula: C18H16O7
Molecular weight: 344.3
Purity: >98% (HPLC)
Appearance: Pale yellow powder.
Solubility: Soluble in DMSO, hot methanol or mixture of methanol and chloroform.
InChiKey: DRRWBCNQOKKKOL-UHFFFAOYSA-N
SMILES: COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)O)OC)O)OC
Description:
Selective inhibitor of 5-lipoxygenase. Anti-proliferative and anticancer compound. Apoptosis and cell cycle arrest inducer. Inhibits ERK1/2, JNK, and NF-kappaB activation and expression of Raf-1 and Ras. PI3K Class I, MKK3/6 and MKK4 inhibitor. Inhibits angiogenesis by blocking STAT3 and VEGF expression. Anti-inflammatory and immunosuppressive agent. Antioxidant. Antidiabetic. Enhances hepatic and plasma glucose metabolism and increases insulin secretion in type 2 diabetic mice. Selective PPARalpha agonist. Neuroprotective.