bs-75208C
[Life Science]
Ophiobolin A
DATASHEET
Formulation Solid
Storage: Stable for 2 years after receipt when stored at -20°C.
Product Information:
CAS Number: 4611-05-6
Molecular formula: C25H36O4
Molecular weight: 400.6
Purity: >95% (HPLC)
Appearance: White solid.
Solubility: Soluble in ethanol, methanol, DMSO or dimethylformamide. Poorly soluble in water.
InChiKey: MWYYLZRWWNBROW-BDZRSQQBSA-N
SMILES: [H]C(=O)C1=C[C@]2([H])[C@](C)(CC[C@@]22O[C@H](C[C@@H]2C)C=C(C)C)C[C@@]2([H])[C@]1([H])C(=O)C[C@@]2(C)O
Molecular formula: C25H36O4
Molecular weight: 400.6
Purity: >95% (HPLC)
Appearance: White solid.
Solubility: Soluble in ethanol, methanol, DMSO or dimethylformamide. Poorly soluble in water.
InChiKey: MWYYLZRWWNBROW-BDZRSQQBSA-N
SMILES: [H]C(=O)C1=C[C@]2([H])[C@](C)(CC[C@@]22O[C@H](C[C@@H]2C)C=C(C)C)C[C@@]2([H])[C@]1([H])C(=O)C[C@@]2(C)O
Description:
Cell permeable, irreversible calmodulin antagonist. Acts by covalently binding to a lysine-rich inhibitory site. Inhibits by blocking the activation of the Ca2+/calmodulin-dependent phosphodiesterase [1-3, 5, 6, 9]. Herbicidal mycotoxin [7]. Phytotoxic, antifungal, antibacterial and nematocidal compound [4, 6, 10]. Anticancer compound. Shown to induce paraptosis-like cell death [11, 12]. Shown to inhibit P-glycoprotein-mediated transport [8]. Disruptor of intracellular sulfhydryl proteostasis, leading to ER stress and dilation.
Size: 100ug,1mg,
Applications: Life Science()
For research use only. Not intended for diagnostic or therapeutic use.