bs-75201C

DATASHEET

Formulation Powder

Storage: Stable for 2 years after receipt when stored at -20°C.

Product Information:

CAS Number: 524-12-9

Molecular formula: C16H10O7

Molecular weight: 314.2

Purity: >98% (HPLC)

Appearance: Yellow to amber crystalline powder.

Solubility: Soluble in DMSO or methanol.

InChiKey: XQDCKJKKMFWXGB-UHFFFAOYSA-N

SMILES: COC1=CC(O)=C2C3=C(C4=C(O3)C=C(O)C(O)=C4)C(=O)OC2=C1

Description:

Cell permeable, selective and irreversible IKKalpha and beta kinase activity inhibitor [2]. NF-kappaB inhibitor. Blocks phosphorylation and degradation of IkappaBalpha [2]. Antihepatotoxic. 5-Lipoxygenase (5-LOX) inhibitor [1, 2]. Anti-inflammatory [2]. HIV-1 integrase inhibitor [3]. Anticancer and antiproliferative compound [4, 5]. Modulates androgen receptor (AR) activation [4]. Apoptosis inducer via downregulation of PKCepsilon [5, 9]. DNA topoisomerase IIalpha inhibitor [6]. G protein-coupled receptor-35 (GPR35) agonist [7]. Inhibits adipogenic differentiation of mesenchymal stem cells (hAMSCs) through ERK pathway [8]. STAT1 protein dephosphorylation inhibitor [10]. Antifibrotic [11].